Research Article
Development of a Murine Infection Model with Leishmania killicki, Responsible for Cutaneous Leishmaniosis in Algeria: Application in Pharmacology
Table 1
Detection of L. major and L. killicki DNA and parasitesin various tissues of BALB/c mice. ND, not determined.
| Leishmania | Tissue or organ | PCR after inoculation/LIT culture | 2 weeks | 4 weeks | 8 weeks | 12 weeks | 16 weeks | 20 weeks |
| L. major | Ear (inoculation site) | + | + | + | +/ND | | | Draining lymph node | + | + | + | +/+ | | | Spleen | + | + | + | +/+ | | | Liver | − | + | + | +/+ | | |
| L. killicki | Ear (inoculation site) | + | + | + | +/ND | + | + | Draining lymph node | − | + | + | +/+ | + | + | Spleen | − | + | + | +/+ | + | + | Liver | − | + | + | +/+ | ND | ND |
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