Proteome Changes of Human Bone Marrow Mesenchymal Stem Cells Induced by 1,4-Benzoquinone

Figure 3

Protein profile difference between 1, 4-BQ-treated and control hBM-MSCs. (a) Comparison of protein profiles by two-dimensional gel electrophoresis between 1,4-BQ treated hBM-MSCs and control. Spots that were differentially expressed were analyzed by LC-MS/MS. (b) Identified proteins with differential expression were cytoplasmic, nuclear, membrane-bound, or secreted. (c) Proteins identified by LC-MS/MS are involved in metabolism (25.00%), cell stress response (15.63%), cell skeleton (12.5%), transcription regulation (12.5%), membrane trafficking (6.25%), signal transduction (6.25%), and miscellaneous function (21.88%).

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