Increased Circulating Advanced Oxidation Protein Products and High-Sensitive Troponin T in Cirrhotic Patients with Chronic Hepatitis C: A Preliminary Report
Table 3
Clinical and biochemical characteristics of patients with liver cirrhosis according to the presence of ascites.
Healthy controls
No ascites
Ascites
()
40
35
53
Age (years)
55 (29–56)
51 (21–74)
58 (24–70)
Esophageal varices (%)
—
17 (49)
39 (74)
Refractory ascites (%)
—
—
11 (21)
Child-Pugh score
—
6 (4–7)
9 (8–10)++
Creatinine (mg/dL)
0.8 (0.7–1.0)
0.9 (0.7–1.4)
1.32 (0.8–2.4)
Albumin (g/L)
45 (36–57)
34 (28–45)
29 (16–40)
MAP (mmHg)
—
88 (85–93)
77+ (73–89)
Plasma renin activity (ng mL−1 h−1)
—
0.48 (0.13–1.4)
1.9++ (0.95–7.6)
Aldosterone (ng/dL)
—
13.2 (5.5–20.9)
33.0+++ (13.7–52.2)
Antidiuretic hormone (pg/mL)
—
4.6 (2.5–5.7)
4.5 (3.6–6.4)
TNF-α (pg/mL)
25.0 (25.5–30.2)
32.3 (31.6–45.6)
55.0 (37.6–64.0)
hs-CRP (mg/L)
1.05 (0.58–2.5)
3.8 (3.1–7.0)
5.9 (4.9–11.0)
hs-TnT (ng/L)
—
5.1 (3.0–6.6)
10.7++ (3.0–18.5)
AOPPs-albumin (μmol/g)
1.7 (0.8–2.7)
2.2 (1.3–4.4)
3.6 (1.9–5.2)
Continuous variables are expressed as median (interquartile range: IQR) and categorical variables as number (percentage). Significance between groups +; ++, +++versus cirrhosis without ascites. AOPPs: advanced oxidation protein products; hs-TnT: high-sensitive troponin T; MAP: mean arterial pressure.
