Research Article
Analysis of Retinal Peripapillary Segmentation in Early Alzheimer’s Disease Patients
Table 2
RNFL thickness and total macular volume.
| | Retinal area of study | | AD group | Control group | % RNFL decrease | value |
| | Peripapillary thickness (μm) | Sector 1 | 101.2 ± 24.4 | 100.0 ± 16.9 | 1.24 | 0.790 | | Sector 2 | 96.8 ± 20.8 | 100.4 ± 14.4 | −3.62 | 0.618 | | Sector 3 | 80.1 ± 22.9 | 90.8 ± 16.0 | −11.85 | 0.084 | | Sector 4 | 60.5 ± 18.3 | 65.4 ± 10.3 | −7.60 | 0.464 | | Sector 5 | 73.7 ± 12.7 | 68.3 ± 11.3 | 7.83 | 0.173 | | Sector 6 | 101.4 ± 23.7 | 99.3 ± 19.0 | 2.02 | 0.790 | | Sector 7 | 119.4 ± 19.1 | 116.3 ± 21.9 | 2.62 | 0.756 | | Sector 8 | 111.7 ± 21.6 | 114.5 ± 24.5 | −2.48 | 0.564 | | Sector 9 | 66.3 ± 18.2 | 67.5 ± 16.5 | −1.80 | 0.877 | | Sector 10 | 60.7 ± 13.8 | 57.3 ± 9.6 | 5.99 | 0.464 | | Sector 11 | 77.0 ± 20.6 | 78.5 ± 14.7 | −1.96 | 0.94 | | Sector 12 | 101.3 ± 27.1 | 110.7 ± 15.8 | −8.45 | 0.335 |
| | Foveal thickness (μm) | Fovea | 221.2 ± 21.6 | 243.7 ± 24.8 | −9.24 | 0.015 |
| | Inner macular quadrant (μm) | Superior area | 283.4 ± 11.1 | 294.9 ± 18.1 | −3.91 | 0.002 | | Inferior area | 279.8 ± 18.1 | 295.8 ± 13.5 | −5.40 | 0.002 | | Nasal area | 285.6 ± 17.2 | 300.1 ± 15.1 | −4.83 | 0.007 | | Temporal area | 273.1 ± 12.7 | 285.2 ± 14.6 | −4.22 | 0.002 |
| | Outer macular quadrant (μm) | Superior area | 245.4 ± 12.5 | 252.1 ± 13.7 | −2.65 | 0.084 | | Inferior area | 242.8 ± 17.4 | 245.2 ± 13.9 | −0.99 | 0.531 | | Nasal area | 263.7 ± 12.1 | 267.5 ± 19.1 | −1.41 | 0.110 | | Temporal area | 228.0 ± 18.8 | 238.5 ± 12.3 | −4.43 | 0.009 |
| | Total macular volume (mm3) | | 7.1 ± 0.3 | 7.3 ± 0.3 | 9.34 | 0.024 |
|
|
Mean value ± SD; [AD, Alzheimer’s disease; RNFL: retinal nerve fiber layer; SD, standard deviation].
|
