Clinical Study
Temozolomide and Radiotherapy versus Radiotherapy Alone in High Grade Gliomas: A Very Long Term Comparative Study and Literature Review
Table 1
Group A and group B: patients’ characteristics.
| | Group A | Group B |
| Patients’ number | 31 | 33 | Age | | | Range | 41–78 years | 26–74 years | Median | 62 years | 57 years | Sex | | | Male | 17 pts | 18 pts | Female | 14 pts | 15 pts | Karnofsky Index | | | Range | 60–90 | 60–90 | Medium | 70 | 70 | Surgery | | | Stereotactic biopsy | 3 pts | 9 pts | Subtotal resection | 18 pts | 12 pts | Total resection | 10 pts | 12 pts | Histology | | | Anaplastic astrocytoma | 11 pts | 10 pts | Glioblastoma multiforme | 20 pts | 23 pts | RT total dose | | | Median | 64 Gy | 63 Gy | Range | 45 Gy–66 Gy | 45 Gy–64 Gy | <50 Gy | 2 pts | 1 pts | ≥50 Gy <60 Gy | 5 pts | 2 pts | ≥60 Gy | 24 pts | 30 pts |
|
|