Extraintestinal Helminth Infection Limits Pathology and Proinflammatory Cytokine Expression during DSS-Induced Ulcerative Colitis: A Role for Alternatively Activated Macrophages and Prostaglandins

Figure 6

T. crassiceps infection reduces the number of inflammatory monocytes during colitis. (a) Representative flow cytometry plots from control mice, DSS-treated mice, and T. crassiceps + DSS mice gated on CD11b⁺ living cells isolated from the circulation. Quantification of circulating (b) CD11b⁺Ly6CCR2⁺ cells and (c) CD11b⁺Ly6CCR2⁻ cells. (d) Percentage of CD11b⁺Ly6CCR2⁺ and CD11b⁺Ly6CCR2⁻ in cells isolated from the colonic lamina propria. Data are representative of two independent experiments. Values are means ± SE ( mice/group). , pooled cells for (d).

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