Use of Adipose-Derived Mesenchymal Stem Cells in Keratoconjunctivitis Sicca in a Canine Model
Table 1
Demographics, STT values, and scores of ocular health.
Dog
Sex
Age
Time (months)
STT
Ocular discharge
Hyperaemia
Corneal changes
1
M
12
0
8/7
2/2
1/1
1/2
3
14/12
1/1
1/1
1/1
6
14/11
0/0
0/1
0/1
9
15/12
0/0
0/0
0/0
2
M
8
0
0/4
2/2
2/2
2/2
3
2/4
1/1
2/1
1/1
6
1/4
1/1
2/1
1/1
9
2/4
1/1
2/1
1/1
3
F
11
0
8/6
1/1
1/1
0/2
3
13/9
0/1
0/1
0/1
6
15/10
0/0
0/1
0/0
9
15/10
0/0
0/0
0/1
4
M
4
0
9/6
1/2
2/2
1/2
3
18/12
0/0
0/1
0/1
6
16/14
0/0
0/1
0/1
9
16/13
0/0
0/1
0/1
5
M
6
0
3/0
2/3
2/3
1/1
3
14/12
1/1
1/1
0/1
6
16/16
0/0
0/0
0/0
9
18/16
0/0
0/0
0/0
6
F
6
0
7/6
2/1
2/2
0/1
3
14/14
1/1
1/1
0/1
6
18/17
0/1
0/1
0/0
9
18/17
0/1
0/0
0/0
7
M
9
0
0/7
3/1
3/2
2/1
3
12/16
1/0
2/0
2/0
6
16/19
0/0
1/0
2/0
9
19/20
0/0
1/0
2/0
8
M
6
0
5/4
1/1
1/1
3/3
3
14/10
0/1
0/0
1/2
6
16/11
0/1
0/0
1/2
9
16/11
0/1
0/0
1/2
9
M
10
0
0/3
3/1
2/1
2/1
3
3/7
2/0
2/1
2/0
6
2/6
2/0
2/1
2/0
9
3/7
2/0
2/0
2/0
10
M
8
0
7/9
1/1
1/1
3/3
3
14/16
0/0
1/0
2/1
6
17/17
0/0
0/0
1/0
9
17/17
0/0
0/0
1/0
11
F
6
0
6/7
1/1
1/1
2/1
3
14/14
1/0
1/0
1/0
6
14/16
0/0
0/0
0/0
9
14/16
0/0
0/0
0/0
12
F
11
0
3/4
2/2
1/0
1/2
3
4/5
1/2
1/0
1/1
6
3/4
1/2
1/0
1/1
9
4/4
1/2
1/0
1/1
M: male; F: female; STT: Schirmer tear test in mm/min. Ocular discharge, hyperaemia, and corneal changes were graded as absent (0), mild (1), moderate (2), or severe (3). The right and left eye data were collected at baseline (0) and 3, 6, and 9 months after cell implantation.
