Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate

Figure 7

PCR-DGGE analysis of the predominant fecal microbiota in mice. (a) PCR-DGGE fingerprints used to analyze the fecal microbiota of the samples from the VaD model group (A), sham-operated group (H), and C. butyricum- (B, 1 × 10⁶ CFU-; C, 1 × 10⁷ CFU-; and D, 1 × 10⁸ CFU-) treated groups. Each lane represents one subject that was randomly selected from each group. The bands marked in the DGGE gel were identified by cloning and sequencing to facilitate the interpretation of the figure. Bands: 1: Bacteroides sp.; 2: Hespellia sp.; 3: Clostridium XVIII sp.; 4: TM7 genera incertae sedis; 5: TM7 genera incertae sedis; 6: Anaerostipes sp.; 7: Barnesiella sp.; 8: Barnesiella sp.; 9: Roseburia sp.; 10: Acinetobacter sp.; 11: unclassified Helicobacteraceae sp.; 12: Streptobacillus sp.; 13: Barnesiella sp.; 14: Clostridium XIVa sp.; 15: Alistipes sp.; 16: unclassified Lachnospiraceae sp.; 17: Lachnospiraceae incertae sedis Alistipes sp.; 18: Anaerostipes sp.; 19: unclassified Porphyromonadaceae sp.; and 20: Butyricimonas sp. (b) Dendrogram of the DGGE profiles shown in (a).

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