Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studies

Table 2

The IC₅₀, expressed as μmol/L, value is the concentration of compound that affords a 50% reduction in cell growth (after a 24 h incubation). J774.A1 = murine monocyte/macrophage cell lines. HEK-293 = human epithelial kidney cell lines. WEHI-164 = murine fibrosarcoma cell lines. 6-MP = 6-mercaptopurine.

cmp	IC50 (𝜇M)
	J774.A1	HEK-293	WEHI-164
HA-Acet	>100	>100	>100
HA	>100	>100	>100
6-MP	1	1.5	1.4