Acute In Vivo Response to an Alternative Implant for Urogynecology

Figure 6

Assessment of new extracellular matrix formation in the samples implanted. Representative light microscopy of sections of abdominal wall of female Sprague-Dawley rat after 3 days of implantation of PLA scaffold on top, previously cultured with and without (control) rat or human ADSCs in DMEM medium for 2 weeks; following immunohistochemistry for anti-collagen I and anti-collagen III antibodies, or Sirius red staining. Scale bars of 0.2 mm for images from 3 days implantation and 0.1 mm for images from 7 days implantation. (S) Sample; (F) Fascia; and (SM) Skeletal Muscle.