Effect of the Zataria multiflora on Systemic Inflammation of Experimental Animals Model of COPD

Table 2

Total number and differential percentage of WBC count in an animal model of COPD treated by three concentrations of Z. multiflora (0.4, 0.8, and 1.6 mg/mL) and dexamethasone (50 µg/mL).

Parameter	Zataria (0.4 mg/mL)	Zataria (0.8 mg/mL)	Zataria (1.6 mg/mL)	Dexamethasone
Total WBC	158.86±2808.33^+++	90.75±1741.66^###	62.8±866.66^++,###,¶¶	216.86±1630
Monocyte	13.33±1.05	10.33±1.83	9.1±0.87	12.5±1.86
Neutrophil	36±1.77^+	33.83±1.28	33.16±1.13^##,¶¶¶	28.66±1.22
Lymphocyte	48.33±2.18^++	54±1.39	67.16±1.94^#,++	58.5±1.77
Eosinophil	2.33 ± 0.33^++	1.83±0.4^#	0.5±0.22^###,¶	0.66±0.33

Values are presented as mean ± SEM. The data of total WBC is their count in one mL of blood and those of each type are the percentage of total WBC. Statistical comparisons between COPD groups treated with Z. multiflora and dexamethasone: ⁺𝑃<0.05, ⁺⁺𝑃<0.01, ⁺⁺⁺𝑃<0.001. Statistical comparison was done using unpaired 𝑡-test. Statistical comparison between the effect of two higher concentrations of the extract (0.8 and 1.6 mg/mL) with its low concentration (0.4 mg/mL): ^#𝑃<0.05, ^##𝑃<0.01, ^###𝑃<0.001. Statistical comparison between the effect of high concentration of the extract (1.6 mg/mL) with its medium concentration (0.8 mg/mL): ^¶𝑃<0.05, ^¶¶𝑃<0.01, ^¶¶¶𝑃<0.001. The statistical comparison was done using ANOVA with Tukey-Kramer multiple posttest.