The Role of 18F-FDG PET/CT in Large-Vessel Vasculitis: Appropriateness of Current Classification Criteria?
Figure 3
Aortitis in Cogan’s syndrome. (a) Transverse hybrid PET/CT slice; pathological uptake in the wall of the aortic arch, more intense in the lateral wall and perivascular space adjacent to the truncus pulmonalis. (SUVmas 12, ESR 52 mm/h, CRP53 mg/L). (b) Follow-up PET/CT showed clearly decreased uptake in the aortic arch after 3 weeks treatment with methyl-Prednisolon i.v. and Prednisolon orally. (SUVmax 4, ESR 11 mm/h, and CRP < 2 mg/L). (c) Second follow-up PET/CT 6 months later (patient was in a stable condition with methotrexate and low-dose prednisone) with again high uptake in the wall of the aortic arch, with higher intensity in the lateral wall and perivascular space adjacent to the truncus pulmonalis. Methotrexate and prednisone were both increased to 20 mg/day (SUVmax 13, ESR 24 mm/h, and CRP 14 mg/L).
