Conversion to Sirolimus Ameliorates Cyclosporine-Induced Nephropathy in the Rat: Focus on Serum, Urine, Gene, and Protein Renal Expression Biomarkers

Figure 3

Serum, urine, and kidney markers of renal function. Creatinine serum levels (a) and clearance (d), blood urea nitrogen levels (c) and clearance (f), glomerular filtration rate (c) and urinary protein (f), kidney lipid peroxidation (malondialdehyde levels) (g), malondialdehyde clearance (h), and kidney weight/body weight ratio (i), at week 3 and week 9 for all treatments. Values are mean ± SEM. ^∗𝑃<0.05 versus control; ^#𝑃<0.05 versus cyclosporin.

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