Variability in Myosteatosis and Insulin Resistance Induced by High-Fat Diet in Mouse Skeletal Muscles
Figure 2
((a)-(b)) In vivo muscle function determined by exhaustion incremental treadmill test and endurance treadmill test. Exhaustion time (a) and endurance time (b) are expressed in min. Control mice: closed bars; HFD mice: white bars. versus control mice, experiments. All data are expressed as mean ± SD. ((c)–(e)) Ex vivo functional parameters of tibialis intact preparations from control (closed bars or closed diamonds) and HFD mice (white bars or closed squares). (c) Twitch time to peak (s); (d) specific tetanic force (g/μL); (e) fatigue index measured as the tetanic force drop for different stimulation frequencies (from 0.03 to 0.9 Hz) compared to the maximal tetanic force (Tf) and expressed in %. versus control mice, experiments. All data are expressed as mean SD.
