Systemic Oxidative Stress and Conversion to Dementia of Elderly Patients with Mild Cognitive Impairment

Table 1

Principal characteristics of nondemented healthy controls, MCI/MCI, MCI/LOAD, and LOAD patients.

	Controls (𝑛=118)	MCI/MCI (𝑛=82)	MCI/LOAD (𝑛=29)	LOAD (𝑛=105)
Age (years)	69.5±9.1	75.9±6.7^c	78.6±5.7^c	78.1±5.5^c
Female gender (%)	72.0^a,b	54.8	51.7	70.1^a,b
Formal education (years)	9.1±4.3	5.9±3.4^c	6.4±4.1^c	5.3±3.5^c
MMSE score (/30)	26.7±2.7	25.8±2.9^b,c	24.1±2.3^a,c	20.4±4.4^a,b,c
GDS (/15)	6.2±3.5	5.9±2.6	5.4±3.4	5.4±3.3
Hypertension (%)	42.1	55.1	54	64.1^c
Diabetes (%)	10.1^a,b	20.1	24.2	13.7^a,b
CVD (%)	9.5^a,b	25.6	25.1	16.7^a,b
Smoking (%)	8.5	5.1	4.7	8.1

Continuous variables are expressed as mean ± standard deviation. MCI/MCI: stable MCI patients; MCI/LOAD: MCI patients converted to LOAD. CVD: cardiovascular disease; MMSE: Mini Mental State Examination; GDS: Global Deterioration Scale.
^a𝑃<0.05 versus MCI/MCI; ^b𝑃<0.05 versus MCI/LOAD; ^c𝑃<0.05 versus controls.