Serum-Free Medium Optimization Based on Trial Design and Support Vector Regression

Table 1

Range of different factors investigated with Plackett-Burman design.

Factors	Level
	−1	1
(ZnSO4)	0.4 mg/L	1 mg/L
(transferrin)	4 mg/L	10 mg/L
(putrescine)	0.4 mg/L	1 mg/L
(BSA)	80 mg/L	200 mg/L
(ferric citrate)	0.3 mmol/L	1 mmol/L
(sodium pyruvate)	0.3 mmol/L	1 mmol/L
(ethanol amine)	2 mg/L	6 mg/L