BioMed Research International

Research Article

Dipeptidyl Peptidase 10 (DPP10789): A Voltage Gated Potassium Channel Associated Protein Is Abnormally Expressed in Alzheimer’s and Other Neurodegenerative Diseases

Table 3

Summary of the DPP10789 positive staining in NFT and plaque-associated dystrophic neurites observed in control and neurodegenerative disease cases.
 Case numberNeuropathological diagnosisFrontal cortexTemporal cortexHippocampusEntorhinal cortexCingulate cortex
TanglePlaqueTanglePlaqueTanglePlaqueTanglePlaqueTanglePlaque
1SA0123AD−++++++++++++++++++++++++++
2SA0126AD+++ ++ ++++++++++++++++++++
3SA0134AD++++−++++++++N/AN/A++++
4SA0143AD+++++ ++ ++++++++++++++
5SA0148AD++++++ −+++++++++++++++++++++
6SA0129Early AD+++++++++++++−−
7SA0069DLBD++++−++++++++++++++ ++
8SA0079DLBD−− −−−++−−−−
9SA0094DLBD−−+++++++++++++++
10SA0063DLBD−−+−++−−−−
11SA0087FTLD−−−−++++++−−−
12SA0035PSP−−+−+−N/AN/A−−
13SA0043PSP++++++++++++−
14SA0106PSP−−−−−−++N/A−−
15SA0136PSP−−−+ −++++++−−
16SA0010Control+−−+ −−−−−+
17SA0013Control−−−−+−−−−−
18SA0021Control−−−−+−+−−−
19SA0030Control −−+−−− N/AN/A++
20SA0031Control−−−−N/AN/AN/AN/A−−
The number of lessons was counted at ×200 magnification under an Olympus BH-2 light microscope (Tokyo, Japan).
N/A: sample not available; −: negative; +: 1–5 lesions/field; ++: 5–10 lesions/field; +++: >10 lesions/field.