Research Article
Molecular Testing for Fragile X: Analysis of 5062 Tests from 1105 Fragile X Families—Performed in 12 Clinical Laboratories in Spain
Table 2
Medical indication for referral.
| | Number of males | Number of females | Total number |
| Patients with ID | | | | With family history of ID | | | | GDD, ID, and autism (all ages) | 97 | 8 | 105 | Studies in ID institutions | 22 | 0 | 22 | With no family history of ID | | | | Children with GDD and or autism | 461 | 55 | 516 | ID in young patients and adults | 113 | 13 | 126 | Patients with normal intelligence | | | | With family history of ID | | | | Relative of a patient with FXS diagnosed in another centre | 30 | 112 | 142 | Individual with history of ID with unknown aetiology in his/her family | 2 | 16 | 18 | With no family history of ID | | | | POI and/or menopause | 0 | 17 | 17 | FXTAS | 10 | 3 | 13 | Unknown reason to be studied | 106 | 40 | 146 |
| Total | 841 | 264 | 1105 |
|
|