Analysis of Genotype 1b Hepatitis C Virus IRES in Serum and Peripheral Blood Mononuclear Cells in Patients Treated with Interferon and Ribavirin

Table 1

Some characteristics of the patients with and without 5′UTR changes during treatment.

	Patients with 5′UTR changes (𝑛=9)	Patients without 5′UTR changes (𝑛=78)
Number of SVR patients	2 (22%)	56 (72%)
HCV viral load at baseline  IU/mL (×10^4)*	181,6 ± 151,9   (range 36,6–281,0)	121,6 ± 125,4  (range 1,7–409,0)
HCV viral load at 12 weeks  IU/mL (×10^2)*	223,8 ± 669,9  (range 0–2010,0)  (𝑛=3)	7,6 ± 28,7  (range 0–209,0)  (𝑛=15)
Number of patients with HCV RNA in PBMC at week 72	7 (78%)	21 (30%)
ALT (IU/L)*	96,9 ± 63,4	107,5 ± 53,3

SVR, sustained virological response; PBMC, peripheral blood mononuclear cell; ALT, alanine transaminase; 𝑛, number of patients.
*Mean ± SD.