Research Article
Molecular and Survival Differences between Familial and Sporadic Gastric Cancers
Table 3
Univariate analysis and multivariate analysis of factors affecting overall survival of GC patients after curative surgery.
| | Univariate analysis | Multivariate analysis | | OR (CI) | P value | OR (CI) | P value |
| Age (<65, ≥65 years) | 1.52 (1.04–2.23) | 0.031 | | | Gender (male, female) | 0.62 (0.42–0.93) | 0.020 | 0.66 (0.44–0.98) | 0.038 | Tumor size (<5 cm, ≥5 cm) | 2.15 (1.47–3.13) | <0.001 | | | Lauren’s classification (intestinal/diffuse) | 0.85 (0.60–1.20) | 0.347 | | | Lymphovascular invasion (−, +) | 3.21 (1.99–5.17) | <0.001 | | | Stromal reaction type (medullary, intermediate, and scirrhous) | 1.47 (1.15–1.87) | 0.002 | | | Family history (−, +) | 0.43 (0.27–0.71) | 0.001 | | | MSI status (MSI-L/S, MSI-H) | 0.52 (0.28–0.96) | 0.035 | 0.50 (0.27–0.93) | 0.029 | TNM stage (I, II, III) | 2.43 (1.89–3.13) | <0.001 | 2.44 (1.89–3.14) | <0.001 |
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OR: odds ratio, CI: confidence interval.
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