Review Article
Integrins in Trabecular Meshwork and Optic Nerve Head: Possible Association with the Pathogenesis of Glaucoma
Table 2
The extracellular matrix and integrins in trabecular meshwork and optic nerve head.
| | Extracellular matrix | Integrin subunits |
| | Trabecular meshwork |
| | Fibronectin | α l | | Laminin | α2 | | Vitronectin | α3 | | Collagen type I | α4 | | Collagen type III | α5 | | Collagen type IV | α6 | | Collagen type V | αv | | Collagen type VI | β1 | | Collagen type XII | β3 | | Fibrillin-1 | β4 | | Decorin | β5 | | Elastin | β6 | | Cochlin | β7 | | Thrombospondin-1 | | | VCAM-1 | | | Myocilin | | | Neuropilin-1 | | | Cadherin | | | -catenin | | | Sphingosine 1 | | | Chondroitin sulfate | | | Heparan sulfate | | | Tenascin | |
| | Optic nerve head |
| | Collagen type I | αl (little expression) | | Collagen type III | α2 | | Collagen type IV | α3 | | Collagen type V | α4 | | Collagen type VI | α5 | | Collagens type VIII | α6 | | Collagens type IX | αv | | Collagen type XVIII | β1 | | Laminin | β2 (little expression) | | Fibronectin | β3 (little expression) | | Tenascin | β4 | | Vitronectin | | | Elastin | | | Chondroitin sulfate | | | Dermatan sulfate | | | Aggrecan | | | Entactin/nidogen | | | Thrombospondin | | | Thrombomodulin | | | Endostatin | | | Cadherin | | | Periostin | | | Cartilage linking protein-1 | | | Fibulin 1 | | | Decorin | | | Perlecan | | | Biglycan | | | Versican | | | Fibromodulin | |
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