Immunohistochemical Expression and Prognostic Value of CD97 and Its Ligand CD55 in Primary Gallbladder Carcinoma

Table 1

Correlation of CD97 and CD55 expressions with conventional clinicopathological parameters in 138 patients with GBC.

Factor	Number	CD97 expression (n, %)		P	CD55 expression (n, %)		P
		Negative	Positive		Negative	Positive
Gender
Male	60	16 (26.7)	44 (73.3)	NS	20 (33.3)	40 (66.7)	NS
Female	78	26 (33.3)	52 (66.7)		28 (35.9)	50 (64.1)
Age at diagnosis		67.2±1.3	69.7±1.8	NS	67.0±1.5	69.8±1.9	NS
Histological grade
G1	18	18 (100.0)	0 (0.0)	0.009	18 (100.0)	0 (0.0)	0.009
G2	84	23 (27.4)	61 (72.6)		26 (31.0)	58 (69.0)
G3	34	1 (2.9)	33 (97.1)		4 (11.8)	30 (88.2)
G4	2	0 (0.0)	2 (100.0)		0 (0.0)	2 (100.0)
Pathologic T stage
T1	32	23 (71.9)	9 (29.1)	0.01	25 (78.1)	7 (21.9)	0.009
T2	64	13 (20.3)	51 (79.7)		17 (26.6)	47 (73.4)
T3	36	6 (16.7)	30 (83.3)		6 (16.7)	30 (83.3)
T4	6	0 (0.0)	6 (100.0)		0 (0.0)	6 (100.0)
Clinical stage
I	60	30 (50.0)	30 (50.0)	0.009	35 (58.3)	25 (41.7)	0.009
II	48	10 (20.8)	38 (79.2)		11 (22.9)	37 (77.1)
III	18	2 (11.1)	16 (88.9)		2 (11.1)	16 (88.9)
IV	12	0 (0.0)	12 (100.0)		0 (0.0)	12 (100.0)
Nodal metastasis
Negative	102	31 (30.4)	71 (69.6)	NS	35 (34.3)	67 (65.7)	NS
Positive	36	11 (30.6)	25 (69.4)		13 (36.1)	23 (63.9)
Distant metastasis
Negative	126	38 (30.2)	88 (69.8)	NS	43 (34.1)	83 (65.9)	NS
Positive	12	4 (33.3)	8 (66.7)		5 (41.7)	7 (58.3)
Venous/lymphatic invasion
Negative	48	28 (58.3)	20 (41.7)	0.009	28 (58.3)	20 (41.7)	0.009
Positive	90	14 (15.6)	76 (84.4)		20 (22.2)	70 (77.8)
Perineural invasion
Negative	66	26 (39.4)	40 (60.6)	NS	22 (33.3)	44 (66.7)	NS
Positive	72	24 (33.3)	48 (66.7)		26 (36.1)	46 (63.9)