Potential ameliorative effects mediated by MSCs in ASD treatment.
|ASD-induced changes in human brain||Potential MSC ameliorative roles seen in preclinical models|
|Abnormal functioning||Improving functional recovery|
|Cerebellum alterations||Integrating in altered brain and restoring damaged functions|
|Decreased number of Purkinje cells (PCs)||Restoring cerebellar PCs|
|Defective cortical organization||Reinforcing cortical plasticity|
|Altered plasticity of dendritic spine morphology||Promoting synaptic plasticity|