New Insights into the Structural Roles of Nebulin in Skeletal Muscle
Figure 3
(a) Wildtype fibers have a regular structure with well-aligned sarcomeres. In nebulin-deficient fibers sarcomeres are misaligned and the Z-disk are out of register. Arrows indicate how Z-disk displacement (X) was defined. (b) Z-disk displacement is significantly increased in nebulin-deficient fibers. (modified from Tonino et al. [27]).
