Review Article

Physiologic Basis and Pathophysiologic Implications of the Diastolic Properties of the Cardiac Muscle

Figure 1

Schematic representation of the end-diastolic pressure-volume relationship (EDPVR) in the absence (a) or presence (b) of diastolic dysfunction. The dashed segment of the EDPVR represents the pressure-volume interval in which an individual remains hemodynamically stable. In (b), the steeper EDPVR narrows the ventricular pressure-volume interval and increases the individual’s susceptibility to hemodynamic decompensation.
807084.fig.001a
(a)
807084.fig.001b
(b)