Review Article
Proportion of Chromosomal Disorders and Their Patterns among Births with Congenital Anomalies in Africa: A Systematic Review and Meta-Analyses
Table 3
Pooled proportion and patterns of chromosomal disorders among births with congenital anomalies in Africa from January, 2000 to October, 2021.
| Variables | Pooled proportion (95% CI) | I2% | value |
| Chromosomal disorders | 8.94 (7.02, 10.86) | 98.8 | <0.001 | Down syndrome | 7.6 (5.70, 9.67) | 98.9 | <0.001 | Edwards’ syndrome | 0.94 (0.49, 1.40) | 31.2 | 0.11 | Patau syndrome | 0.92 (0.34, 1.51) | 49.7 | 0.03 | Turner syndrome | 1.51 (1.3, 1.71) | — | 0.56 | Unclassified chromosomal disorders | 1.78 (0.97, 2.60) | — | 0.36 | Chromosomal deletions | 0.92 (0.37, 1.47) | 82.3 | <0.001 |
|
|
Unclassified chromosomal disorders—others and unclassified chromosomal anomalies. |