Review Article

Proportion of Chromosomal Disorders and Their Patterns among Births with Congenital Anomalies in Africa: A Systematic Review and Meta-Analyses

Table 3

Pooled proportion and patterns of chromosomal disorders among births with congenital anomalies in Africa from January, 2000 to October, 2021.

VariablesPooled proportion (95% CI)I2% value

Chromosomal disorders8.94 (7.02, 10.86)98.8<0.001
Down syndrome7.6 (5.70, 9.67)98.9<0.001
Edwards’ syndrome0.94 (0.49, 1.40)31.20.11
Patau syndrome0.92 (0.34, 1.51)49.70.03
Turner syndrome1.51 (1.3, 1.71)0.56
Unclassified chromosomal disorders1.78 (0.97, 2.60)0.36
Chromosomal deletions0.92 (0.37, 1.47)82.3<0.001

Unclassified chromosomal disorders—others and unclassified chromosomal anomalies.