Proportion of Chromosomal Disorders and Their Patterns among Births with Congenital Anomalies in Africa: A Systematic Review and Meta-Analyses

Table 2

Subgroup analysis on the pooled proportion and patterns of chromosomal disorders among births with congenital anomalies: by country, region, and year of publication in Africa from January, 2000 to October, 2021.

Variables	Characteristics	Pooled prevalence	I^2 ( value)
By country	Libya	30.12 (13.17, 47.07)	96.9% (<0.001)
	DRC	19.3 (15.5, 23.03)	—
	Cameroon	18.18 (10.58, 23.7)	—
	Egypt	10.91 (4.04, 17.76)	99.5% (<0.001)
	Morocco	10.41 (5.8, 14.8)	80.7% (0.001)
By region	Central Africa	19.08% (95% CI: 15.74, 22.43)	—
	North Africa	15.06% (95% CI: 10.65, 19.47)	98.9 (<0.001)
	Southern Africa	5.4.0% (95% CI: 2.01, 8.79)	99% (<0.001)
	East Africa	4.880% (95% CI: 2.56, 7.20)	91.1% (<0.001)
	West Africa	4.03% (95% CI: 2.88, 5.18)	38.7% (=0.05)
By year of publication	2000–2014	8.32 (95% CI: 4.23, 12.15)	99.5% ()
	2015–2021	8.53% (95% CI: 6.95, 10.12)	93.8% ()

DRC-Democratic Republic of Congo.