Palatable Levocetirizine Dihydrochloride Solid Dispersed Fast-Dissolving Films: Formulation and In Vitro and In Vivo Characterization

Table 4

Stability studies of the optimized fast-dissolving films (LF-7) of levocetirizine dihydrochloride.

Evaluation parameter	Fresh	One month	Three months
Weight variation (mg)	30.29	30.09	30.20
	±2.01	±2.99	±2.96
Thickness (μm)	27.46	26.66	27.67
	±1.09	±2.16	±3.15
In-vitro disintegration (sec.)	25	21	35
	±2.00	±3.41	±1.35
Drug content	98.31	99.01	95.24
Uniformity (%)	±1.02	±0.055	±0.048
In-vitro drug release (%)	99.22	101.82	97.12
	±2.20	±0.65	±1.95

(n = 3; mean ± SD).