[Retracted] PASS-Predicted Hepatoprotective Activity of Caesalpinia sappan in Thioacetamide-Induced Liver Fibrosis in Rats

Table 4

Effects of CS extract treatment on the level of MMP-2, MMP-9, and TIMP-1 in the liver tissue at the end of 12 weeks.

Group	MMP-2 (ng/mL)	MMP-9 (ng/mL)	TIMP-1 (ng/mL)
Normal	2.57±0.4^b	8.31±1.2^b	1.91±0.79^b
TAA	8.44±1.06^a	46.57±4.7^a	7.81±0.85^a
CS100	2.44±0.43^b	8.57±8.11^b	1.83±0.38^b
CS300	2.37±0.65^b	8.8±0.75^b	2.04±0.67^b
CS100 + TAA	6.43±0.569^a,b	22.76±1.78^a,b	4.78±1.01
CS300 + TAA	4.87±0.77^a,b	15.51±2.44^a,b	3.05±0.63
SY + TAA	3.38±0.525^b	13.84±2.8^a,b	2.12±0.48^b

The data were stated as mean ± S.E.M. Means with different superscripts are significantly different. ^a𝑃<0.05 versus normal control group and ^b𝑃<0.05 versus TAA control group. SY stands for Silymarin (standard hepatoprotective drug).