Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo
Table 2
Demographic, body mass index, arterialized plasma and abdominal subcutaneous adipose tissue (AbScAT) venous plasma hepcidin concentrations, and in vivo net regional hepcidin release from AbScAT in obese () and lean () subjects.
Gender
Age (years)
BMI (kg/m2)
Arterialized plasma hepcidin (ng/mL)
AbScAT venous plasma hepcidin (ng/mL)
Net regional AbScAT hepcidin release (ngยท100โg adipose tissueโ1 ยท minโ1)*
Male
51
36.4
9.9
7.5
โ9.219912
Male
46
41.3
59.8
67.9
16.0832952
Male
48
41.5
140
133.6
โ19.305216
Male
44
35.9
148.7
144.4
โ17.088888
Male
40
30.2
76.2
59.1
โ65.28951
Male
44
22.3
9
7.4
โ5.53728
Male
32
24.3
119
99.3
โ18.024318
Female
56
33.8
74.1
61.6
โ9.828
Female
39
36.1
59.1
61.4
5.231787
Female
43
35.4
30.4
31.9
8.0784
Female
45
40.4
20.4
15.3
โ17.136
Female
45
21.7
21
19.3
โ1.978596
Female
57
21.3
93.9
84.9
NA
Female
41
24.7
90.6
93.5
4.871826
Female
56
23.9
6.4
6.2
โ0.450996
Female
43
22.8
8.5
8
โ1.96371
Female
40
21
12.9
19.2
14.829696
Female
40
21.6
196.3
167
โ144.338832
All biochemical analysis was performed on morning fasting samples.
*Net regional hepcidin release = [(AbScAT venous plasma hepcidin] โ (Arterialized plasma hepcidin)] * AbScAT plasma flow. BMI: body mass index; NA: not available due to unreliable adipose tissue blood flow calculation.
