Research Article

Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo

Table 1

Demographic and clinical characteristics of Caucasian obese and lean adults ( 𝑛 = 1 8 ).

Obese ( 𝑛 = 9 )Lean ( 𝑛 = 9 )

Age (years)45.8 ± 5.344.2 ± 7.9
Gender (male/female) [% (n)]55.6 ( 𝑛 = 5 )/44.4 ( 𝑛 = 4 )22.2 ( 𝑛 = 2 )/77.78 ( 𝑛 = 7 )
Body mass index (kg/m2)36.8 ± 3.722.6 ± 1.4
Waist circumference (cm)115.1 ± 10.977.7 ± 5.9
Arterialized plasma hepcidin (ng/mL)68.7 ± 48.762.0 ± 67.1
AbScAT venous plasma hepcidin (ng/mL)64.7 ± 47.456.1 ± 57.3
Hematocrit (%)41.4 ± 0.0339.3 ± 0.05

All biochemical analysis was performed on fasted samples.
Data are presented as means ± standard deviations or as percentages.
Differences between groups were assessed using Student’s t-test for continuous variables and Fisher’s exact test for categorical variables.
Differed significantly between obese and lean participants ( 𝑃 < 0 . 0 0 0 1 ).
AbScAT: Abdominal subcutaneous adipose tissue.