Research Article

Tuberculosis Test Usage and Medical Expenditures from Outpatient Insurance Claims Data, 2013

Table 1

Current procedural terminology (CPT) codes and their description for the TB-specific and the nonspecific TB tests.

CPT codeDescription (source: American Medical Association online CPT search [5])

TB-specific tests
86480Tuberculosis test, cell mediated immunity antigen response measurement; gamma interferon (QuantiFERON-TB Gold In-Tube [QFT-GIT]
86481Tuberculosis test, cell mediated immunity antigen response measurement; enumeration of gamma interferon-producing T-cells in cell suspension (T-SPOT.TB [T-Spot]
86580Skin test; tuberculosis, intradermal
87555Infectious agent detection by nucleic acid (DNA or RNA); Mycobacterium tuberculosis, direct probe technique
87556Infectious agent detection by nucleic acid (DNA or RNA); Mycobacterium tuberculosis, amplified probe technique
87557Infectious agent detection by nucleic acid (DNA or RNA); Mycobacterium tuberculosis, quantification

Nonspecific TB tests
71020Radiologic examination, chest, 2 views, frontal and lateral
71260Computed tomography, thorax; with contrast material(s)
87116Culture, tubercle, or other acid-fast bacilli (e.g., TB, AFB, and mycobacteria) any source, with isolation and presumptive identification of isolates
87118Culture, mycobacterial, definitive identification, each isolate
87143Culture, typing; gas liquid chromatography (GLC) or high pressure liquid chromatography (HPLC) method
87149Culture, typing; identification by nucleic acid (DNA or RNA) probe, direct probe technique, per culture or isolate, each organism probed
87150Culture, typing; identification by nucleic acid (DNA or RNA) probe, amplified probe technique, per culture or isolate, each organism probed
87153Culture, typing; identification by nucleic acid sequencing method, each isolate (e.g., sequencing of the 16S rRNA gene)
87158Culture, typing; other methods
87188Susceptibility studies, antimicrobial agent; macrobroth dilution method, each agent
87190Susceptibility studies, antimicrobial agent; mycobacteria, proportion method, each agent
87206Smear, primary source with interpretation; fluorescent and/or acid fast stain for bacteria, fungi, parasites, viruses, or cell types
87550Infectious agent detection by nucleic acid (DNA or RNA); mycobacteria species, direct probe technique
87551Infectious agent detection by nucleic acid (DNA or RNA); mycobacteria species, amplified probe technique
87552Infectious agent detection by nucleic acid (DNA or RNA); mycobacteria species, quantification
87798Infectious agent detection by nucleic acid (DNA or RNA), not otherwise specified; amplified probe technique, each organism
87799Infectious agent detection by nucleic acid (DNA or RNA), not otherwise specified; quantification, each organism

The brand names for the respective IGRA testing method CPT codes (i.e., QuantiFERON-TB Gold In-Tube [QFT-GIT] for 86480 and T-SPOT.TB [T-Spot] for 86481) were used because they were the only IGRA tests approved by the Food and Drug Administration (FDA) as of 2013 [7].