Stratified Threshold Values of QuantiFERON Assay for Diagnosing Tuberculosis Infection in Immunocompromised Populations
Table 1
Demographic and baseline clinical characteristics of pulmonary tuberculosis patients.
Total, n
727
Age, median, range
63
15–97
Female, n, %
208
28.8
Nationality (other than Japanese), n, %
9
1.2
Sputum smear statusa, n, %
0
167
23.0
1+
187
25.7
2+
113
15.5
3+
252
34.7
unknown
7
1.0
Lung cavitary lesion, n (%)
276
38.0
Underlying preexisting conditionsb, n, %
Administration of immunosuppressant before TB onsetc
39
5.4
Malignant diseases
44
6.1
Serum albumin less than 3.0 g/dL
248
34.1
Bedridden
78
10.7
Diabetes mellitus
69
9.5
HIV positive
8
1.1
Liver cirrhosis
5
0.7
Renal failure
5
0.7
History of cerebral infarction
17
2.3
Silicosis
3
0.4
Dementia
45
6.2
Alcoholism
15
2.1
Homeless
34
4.7
Drug abuser
0
0.0
Note. aSmear by sputum microscopy: 0 (no acid fast bacilli (AFB) on smear), 1+ (1–99 AFB per 100 field), 2+ (1–10 AFB per field), and 3+ (more than 10 AFB per field).
bMore than one condition can coexist in the same patient.
cIncluding chronic systemic steroids, antitumor necrosis alpha agents and immunosuppressive agents.
