Review Article
Pathologic Etiologies of Late and Very Late Stent Thrombosis following First-Generation Drug-Eluting Stent Placement
Table 1
Incidence and underlying causes of late/very late stent thrombosis in SES and PES.
| | SES | PES | value |
| Incidence of late/very late ST | 16/77 (21%) | 25/94 (27%) | 0.47 | Underlying causes of late/very late ST | | | | AMI, penetration of the necrotic core | 5 (31%) | 5 (20%) | 0.47 | Bifurcation stenting | 1 (6%) | 9 (36%) | 0.06 | Long/overlapping stents | 0 (0%) | 2 (8%) | 0.50 | Stent underexpansion | 1 (6%) | 1 (4%) | 1.00 | Isolated uncovered struts | 2 (13%) | 1 (4%) | 0.55 | Localized hypersensitivity | 7 (44%) | 0 (0%) | 0.0005 | Malapposition from excessive fibrin deposition | 0 (0%) | 7 (28%) | 0.03 |
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AMI: acute myocardial infarction; PES: paclitaxel-eluting stents; SES: sirolimus-eluting stents; ST: stent thrombosis (Reproduced with permission from [49].)
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