Clinical Outcomes after Intravenous Alteplase in Elderly Patients with Acute Ischaemic Stroke: A Retrospective Analysis of Patients Treated at a Tertiary Neurology Centre in England from 2013 to 2018

Table 2

Clinical and safety outcomes in the groups of aged >80 and aged ≤80 according to treatment window.

Outcomes	Time to treatment 0–3 h			Time to treatment 3–4.5 h
			value			value
Mortality rate, No. (%)	26 (6%)	22 (10%)	0.08	7 (6%)	3 (4%)	0.7
Symptomatic ICH rate, No. (%)	18 (4.5%)	16 (7.5%)	0.11	6 (4.9%)	4 (6%)	0.76
Favorable outcome, No. (%)	136 (34%)	33 (16%)	<0.0001	50 (41%)	5 (7%)	<0.0001
Independence, No. (%)	186 (46%)	54 (26%)	<0.0001	62 (50%)	15 (22%)	0.0001
Neurological improvement, No. (%)	152 (41.8%)	73 (37.4%)	0.37	34 (31.8%)	21 (35.6%)	0.73

At hospital discharge; modified Rankin at hospital discharge; modified Rankin at hospital discharge; baseline National Institutes of Health Stroke Scale score or remained at ≤1 24 hours after intravenous thrombolysis; No.: number; ICH: intracerebral haemorrhage.