Research Article
Acute Cholecystitis in Very Elderly Patients: Disease Management, Outcomes, and Risk Factors for Complications
Table 1
Patients’ demographic and clinical characteristics, received treatment, and outcomes.
| | Characteristics | Overall () | 80–85.4 years () | 85.4–90 years () | |
| | Age, years | 85.7 ± 4 | 82.5 ± 1 | 89.0 ± 3 | <0.001 | | Male gender | 184 (53) | 93 (53.5) | 91 (52.3) | 0.8 | | Diabetes | 104 (30) | 52 (29.9) | 52 (29.9) | 1 | | ASA III | 193 (55.5) | 93 (53.4) | 100 (57.5) | 0.4 | | ASA IV | 43 (12.5) | 17 (9.8) | 26 (14.9) | 0.1 | | Anticoagulation therapy | 77 (22.1) | 38 (21.8) | 39 (22.4) | 0.9 | | History of biliary disease | 40 (11.5) | 20 (11.5) | 20 (11.5) | 1 | | Choledocholithiasis | 28 (8.0) | 11 (6.3) | 17 (9.8) | 0.2 | | Symptom days at admission | 3.1 ± 3.9 | 2.8 ± 3.3 | 3.5 ± 4.6 | 0.1 | | AC grade | — | — | — | 0.1 | | Grade I | 106 (30.5) | 45 (25.9) | 61 (35.1) | | | Grade II | 189 (54.3) | 104 (59.8) | 85 (48.9) | | | Grade III | 53 (15.2) | 25 (14.4) | 28 (16.1) | | | Received treatment | | | | | | Antibiotics only | 210 (60.3) | 91 (52.3) | 119 (68.4) | 0.006 | | Cholecystostomy (<48 hrs) | 25 (7.2) | 5 (2.9) | 20 (11.5) | 0.002 | | Early cholecystectomy (<48 hrs) | 113 (32.5) | 74 (42.5) | 34 (19.5) | <0.001 | | Total cholecystectomy | 119 (34.2) | 80 (46.0) | 39 (22.4) | <0.001 | | Laparoscopic cholecystectomy | 104 (87.4) | 72 (90.0) | 32 (82.1) | 0.2 | | Conversion to open surgery | 12 (11.5) | 9 (12.5) | 3 (9.4) | 0.6 | | Days of antibiotic therapy | 7.5 ± 3 | 7.3 ± 3.4 | 7.6 ± 3.3 | 0.4 | | Days of hospital stay | 6.5 ± 5 | 6.0 ± 4.1 | 6.7 ± 6.0 | 0.6 | | 30-day complications | 60 (17.2) | 32 (18.4) | 28 (16.1) | 0.5 | | 30-day mortality | 13 (3.7) | 4 (2.3) | 9 (5.2) | 0.1 | | 30-day readmission | 14 (4.2) | 10 (5.9) | 4 (2.4) | 0.1 | | 2-year AC recurrence | 49 (22.1) | 20 (21.7) | 29 (22.3) | 0.9 | | 2-year biliary readmission | 77 (34.7) | 34 (37.0) | 43 (33.1) | 0.5 |
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