Research Article
A Crossover Comparison of the Sensitivity and the Specificity between BIS and AEP in Predicting Unconsciousness in General Anesthesia
Table 11
Propofol/sevoflurane concentration, BIS/AEP values, and prediction probabilities at unconsciousness (mean (95% CI).
| | EC5 | EC50 | EC95 | Sensitivity (%) | Specificity (%) | Prediction probability | Propofol | Sevoflurane | Propofol | Sevoflurane | Propofol | Sevoflurane | Propofol | Sevoflurane | Propofol | Sevoflurane | Propofol | Sevoflurane |
| Blood concentration (g/ml)/Fi (%) | 1.9 | 2.3 | 3.2 (3–3.4) | 3.3 (3.2–3.4) | 4.5 | 4.3 | 85 | 79 | 81 | 66 | 0.83 | 0.72 | Effect-site concentration (g/ml)/ET (%) | 1.3 | 1.1 | 2.3 (2.2–2.4) | 2.2 (2.1–2.3) | 3.3 | 3.3 | 83 | 79 | 73 | 75 | 0.78 | 0.77 | BIS | 77 | 93 | 57 (55–59) | 58 (54–61) | 37 | 23 | 79 | 77 | 72 | 77 | 0.76 | 0.77 | AEP | 61 | 85 | 32 (30–35) | 48 (45–52) | 4 | 12 | 71 | 68 | 79 | 82 | 0.75 | 0.75 |
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