I have seen many cases of people groaning and shouting in their sleep, some who choke, and others jump from their bed and run outside and remain out of their mind till they wake, when they are as healthy and sane as they were before although perhaps rather pale and weak. These things are not isolated events but frequent occurrences. There are many other remarkable afflictions of various sorts, but it would take too long to describe them. Sleep has long been interesting to physicians, for example, Hippocrates in his book titled On the Sacred Disease. Sleep-related breathing disorders are among the most prevalent and clinically important sleep-wake disorders and can be divided into those arising from disorders of the respiratory apparatus and airway, and those with an inadequate neural drive for breathing. The main focus of this special issue will be on the new and existing findings on sleep-related breathing disorders and to their cognitive, metabolic, and cardiovascular consequences. The issue will become an international forum for researchers to summarize the most recent developments and ideas in the field.

We particularly take an interest in manuscripts that report mechanisms and predictors for daytime and residual sleepiness in obstructive sleep apnea, cognitive and mood impairment, and common pathways between obstructive sleep apnea and cardiovascular and metabolic disorders, diabetes mellitus, erectile dysfunction, and obesity as well as central sleep apnea, complex apnea, and obesity hypoventilation syndrome. Reviews that summarize the results of clinical trials referring to effectiveness and to treatment response are welcome. Moreover, papers dealing with new diagnostic tools, optimal treatment options, followup and compliance with therapy, predictors, and markers for severity and treatment response. Potential topics include, but are not limited to:

• Obstructive sleep apnea and residual daytime sleepiness
• Obstructive sleep apnea, cognitive function, and mood impairment
• Obstructive sleep apnea diabetes and metabolic syndrome
• Obstructive sleep apnea and cardiovascular consequences with emphasis on morbidity and mortality
• Obstructive sleep apnea and weight loss
• Sleep apnea and stable narcotic therapy for chronic pain patients
• Obstructive sleep apnea and erectile dysfunction
• Obstructive sleep apnea, initiation and followup of treatment options
• Sleep apnea and differentiating treatment modalities: CPAP, BiPAP, auto-PAP, and ASV
• Obesity hypoventilation syndrome

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/sd/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: