Nocturnal Continuous Positive Airway Pressure (nCPAP) Decreases High-Sensitivity C-Reactive Protein (hs-CRP) in Obstructive Sleep Apnea-Hypopnea Syndrome

Table 1

General characteristics of the four study groups.

	Groups				Total
Variables/groups	G1 ()	G2 ()	G3 ()	G4 ()		G1 vs. G2	G1 vs. G3	G1 vs. G4	G3 vs. G4
Mean age (years)						NS	NS	NS	NS
Males/females	0.9	1.04	1.4	0.72	1	NS	NS	NS	NS
Smoking status (%)	4 (19)	12 (27.9)	8 (33.3)	4 (21.1)	16 (25)	NS	NS	NS	NS
Alcoholism (%)	1 (4.8)	3 (7)	3 (12.5)	0 (0)	4 (6.3)	NS	NS	NS	NS
ESS						0.013	NS	NS	0.015
BMI (kg/m^2)						NS	NS	NS	0.032
CP (cm)						0.001	0.001	0.001	NS
WHR						0.024	NS	NS	NS
Mean SBP (mmHg)						NS	NS	<10^-4	<10^-4
FVC (L)						NS	NS	NS	NS
FEV1 (L)						NS	NS	NS	NS
FEV1/FVC (%)						NS	NS	NS	NS
AHI (events/h)	2.2 [0.9-4.8]	25.9 [7.1-78.9]	26 [8-77.9]	25.3 [7.1-78.9]	15.85 [0.9-78.9]	<10^-3	<10^-3	<10^-3	NS
Mean SpO2 (%)						<10^-3	<10^-3	<10^-3	0.034
Min SpO2 (%)						<10^-3	<10^-3	<10^-3	NS
ODI (events/h)	1.8 [0-6.7]	20.2 [1-84.1]	15.85 [1-74.3]	23.2 [1.6-84.1]	7.15 [0-84.1]	<10^-3	<10^-3	<10^-3	NS
TST90 (%)	0.0001 [0-3]	7.2 [0-82.3]	6.25 [0-27.6]	9.3 [0-82.3]	3.7 [0-82.3]	<10^-3	<10^-3	<10^-3	NS
Serum glucose level (mmol/L)						0.029	NS	NS	NS
HbA1c level (%)						NS	NS	NS	NS
Serum urea level (mmol/l)						NS	NS	NS	NS
Serum creatinine level (mmol/l)						NS	NS	NS	NS
Creatinine clearance (ml/min)						NS	NS	NS	NS

G1: controls. G2: patients with obstructive apnea-hypopnea syndrome (OAHS). G3: normotensive OAHS patients. G4: hypertensive OAHS patients. : number. ESS: Epworth sleepiness scale. BMI: body mass index. CP: cervical perimeter. WHR: waist-hip ratio. SBP: systolic blood pressure. FVC: forced vital capacity. FEV1: forced expiratory volume in 1 second. AHI: apnea-hypopnea index. SpO₂: transcutaneous oxygen saturation. ODI: oxygen desaturation index. TST90: total sleep time with . HbA1c: glycated hemoglobin. Italic values indicate statistically significant difference.