Research Article

Systems Biology Genetic Approach Identifies Serotonin Pathway as a Possible Target for Obstructive Sleep Apnea: Results from a Literature Search Review

Figure 2

The genes identified from the enrichment analysis were significantly associated with OSA comorbidities. Ingenuity Pathway Analysis was used to create gene-disease network. The selected candidate genes () were significantly associated with anxiety disorders (), obesity (), obsessive-compulsive disorder (), dyslipidemia (), social anxiety disorder (), type 2 diabetes (), blood pressure (), eating disorder (), depression (), and metabolic syndrome ().