Regulation of Dopamine Uptake by Vasoactive Peptides in the Kidney

Figure 8

Schematic representation of the mechanism by which CNP and Ang-(1-7) ((a) and (b), resp.) could enhance dopamine tubular transport in proximal tubule cells, by stimulation of extraneuronal uptake. OCTs: organic cationic transporters. Black circles: dopamine; gray triangle: CNP. Black square: Ang-(1-7). Full arrows and +: stimulation; full arrows and −: inhibition; dot arrows: no effect; ?: hypothetical mechanism.