Primary Injuries and Secondary Organ Failures in Trauma Patients with Acute Kidney Injury Treated with Continuous Renal Replacement Therapy
Table 3
Subgroups analyses of trauma patients with acute kidney injury treated with continuous renal replacement therapy ().
Early versus late initiation of CRRT
Days from trauma to initiation of CRRT ≤5 days (early) or >5 days (late)
Overall ()
Early ()
Late ()
=
PRBC transfusions (number)
11 (4–26)
10 (3–23)
13.5 (5.5–26.25)
0.45
Serum creatine kinase (U/L)
3814 (575–25487)
9643 (2775–43434)
317 (101–2499)
<0.01
Multiple organ failure
27 (64)
16 (69)
11 (58)
0.43
Mortality
15 (36)
6 (26)
9 (47)
0.15
Oliguric versus nonoliguric acute kidney injury
Daily diuresis at initiation of CRRT ≤500 mL (oliguric) or >500 mL (nonoliguric)
Overall ()
Oliguric ()
Nonoliguric ()
=
Diuresis admission day (mL)
2420 (1610–3580)
2020 (1375–2808)
2666 (1858–3680)
0.81
Days to CRRT
5 (3–11)
4 (2–6.25)
7 (3–13)
<0.01
Multiple organ failure
27 (64)
13 (81)
14 (58)
0.07
Mortality
15 (36)
7 (44)
8 (31)
0.39
Categorical data are presented as number (percent) and compared using 2-sided Pearson’s Chi-squared test. Continuous data are presented as median (interquartile range) and compared using 2-tailed Mann-Whitney test. CRRT: continuous renal replacement therapy. PRBC: packed red blood cell. Days from traumatic insult to initiation of CRRT.