Research Article

Primary Injuries and Secondary Organ Failures in Trauma Patients with Acute Kidney Injury Treated with Continuous Renal Replacement Therapy

Table 3

Subgroups analyses of trauma patients with acute kidney injury treated with continuous renal replacement therapy ().

Early versus late initiation of CRRT
Days from trauma to initiation of CRRT ≤5 days (early) or >5 days (late)

Overall ()Early ()Late ()=

PRBC transfusions (number)11 (4–26)10 (3–23)13.5 (5.5–26.25)0.45
Serum creatine kinase (U/L)3814 (575–25487)9643 (2775–43434)317 (101–2499) <0.01
Multiple organ failure 27 (64)16 (69)11 (58)0.43
Mortality15 (36)6 (26)9 (47)0.15

Oliguric versus nonoliguric acute kidney injury
Daily diuresis at initiation of CRRT ≤500 mL (oliguric) or >500 mL (nonoliguric)

Overall ()Oliguric ()Nonoliguric ()=

Diuresis admission day (mL)2420 (1610–3580)2020 (1375–2808)2666 (1858–3680)0.81
Days to CRRT5 (3–11)4 (2–6.25)7 (3–13)<0.01
Multiple organ failure27 (64)13 (81)14 (58)0.07
Mortality15 (36)7 (44)8 (31)0.39

Categorical data are presented as number (percent) and compared using 2-sided Pearson’s Chi-squared test. Continuous data are presented as median (interquartile range) and compared using 2-tailed Mann-Whitney test. CRRT: continuous renal replacement therapy. PRBC: packed red blood cell.
Days from traumatic insult to initiation of CRRT.