Establishing and Validating an Aging-Related Prognostic Signature in Osteosarcoma

Figure 4

Construction of the ARG-based signature to predict prognosis of osteosarcoma in the TCGA cohort. (a) Volcano plot for ARGs in osteosarcoma. (b) The LASSO analysis was used to identify the prognostic variables and develop the predictive models. (c) Plots of the produced coefficient distributions for the logarithmic (lambda) series for parameter selection (lambda). (d) Multivariate Cox regression identification of an ARG-based risk signature for osteosarcoma prognosis prediction.

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