Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors

<div>hBMMSC-Exo promote tumor growth in vivo. (a) Representative example of BALB/c-nu mice after transplantation with K562 cells and hBMMSC-Exo by subcutaneous injection. (b) Gross observation of the isolated tumors on day 40 after implantation. (c) Tumor incidence. hBMMSC-Exo significantly increased the tumor incidence. (d) Tumor growth curves. Tumor growth was faster in group K562 cells mixed with hBMMSC-Exo. (e) Representative micrographs of TUNEL staining. 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Stem Cells International

fig6

Figure 6

Figure 6: Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors 

Figure 6 | Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors 