Hypoxia-Preconditioned Wharton’s Jelly-Derived Mesenchymal Stem Cells Mitigate Stress-Induced Apoptosis and Ameliorate Human Islet Survival and Function in Direct Contact Coculture System

<div>VEGF secretion and mRNA expression in human islets cocultured with Hpc-MSCs and Nc-MSCs. (a) VEGF mRNA expression and (b) VEGF secretion in the islet groups. 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Nc-MSCs: normoxia condition mesenchymal stem cells; Hpc-MSCs: hypoxia preconditioning MSCs; D: direct coculture; I: indirect coculture.</div>

Stem Cells International

fig10

Figure 10

Figure 10: Hypoxia-Preconditioned Wharton’s Jelly-Derived Mesenchymal Stem Cells Mitigate Stress-Induced Apoptosis and Ameliorate Human Islet Survival and Function in Direct Contact Coculture System 

Figure 10 | Hypoxia-Preconditioned Wharton’s Jelly-Derived Mesenchymal Stem Cells Mitigate Stress-Induced Apoptosis and Ameliorate Human Islet Survival and Function in Direct Contact Coculture System 