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Stem Cells International
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2019
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Article
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Tab 1
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Review Article
Enhancing Mesenchymal Stromal Cell Immunomodulation for Treating Conditions Influenced by the Immune System
Table 1
Clinical trials of MSCs on diseases mediated by the immune system.
Trial no.
Phase
Commencement year
Targeted disease
Status
Patient enrollment (
)
Country
NCT00447460
I/II
2007
Graft vs. host disease (GvHD)
Completed [
100
]
15
Spain
NCT01522716
I
2011
Unknown (NRP)
11
Sweden
NCT01764100
I
2013
Completed [
101
]
40
Italy
NCT02032446
I/II
Recruiting
47 (estimated)
NCT02291770
III
2014
Unknown (NRP)
130 (estimated)
China
NCT02055625
I/II
Suspended (NRP)
11
Sweden
NCT02359929
I
2015
Recruiting
24 (estimated)
USA
NCT01741857
I/II
Systemic lupus erythematosus (SLE)
Completed [
102
]
40
China
NCT03171194
I
Active, not recruiting
6 (estimated)
USA
NCT03673748
II
2019
SLE/lupus nephritis
Not yet recruiting
36 (estimated)
Spain
NCT00781872
I/II
2006
Multiple sclerosis (MS)
Completed [
103
]
20
Israel
NCT00395200
I/II
2008
Completed [
104
,
105
]
10
UK
NCT01730547
I/II
2013
Unknown
15 (estimated)
Sweden
NCT02495766
I/II
2015
Unknown
8 (estimated)
Spain
NCT03799718
II
2019
Not yet recruiting
20 (estimated)
USA
NCT02893306
II
2012
Type 1 diabetes mellitus (T1DM)
Unknown (NRP)
10
Chile
NCT02940418
I
2017
Recruiting
20 (estimated)
Jordan
NCT03406585
I/II
Recruiting
24 (estimated)
Sweden
NCT02249676
II
2013
Devic syndrome/neuromyelitis optica
Completed
15
China
NCT01659762
I
2012
Crohn’s disease
Completed [
106
]
16
USA
NRP: no results posted.