Mesenchymal Stem Cells Alleviate Moderate-to-Severe Psoriasis by Reducing the Production of Type I Interferon (IFN-I) by Plasmacytoid Dendritic Cells (pDCs)
Effector cell infiltration of the dermis of the skin was significantly decreased in MSC-treated mice. IHC analysis of infiltrating CD3+ T cells, Gr-1+ neutrophils, and IL-17+ cells in the skin on day 6 and 8. Scale bar, 100 μm.
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