(Mesenchymal) Stem Cell-Based Therapy in Cisplatin-Induced Acute Kidney Injury Animal Model: Risk of Immunogenicity and Tumorigenicity

Table 5

Body weight, relative weight of organs, and blood parameters in BALB/cOlaHsd mice 3 months after hMSC transplantation.

Parameter	CIS	hMSCs	Healthy
WBC (10^3/mm^3)	8.1	10.9	10.1
RBC (10^6/mm^3)	7.46	10.35	9.46
PLT (10^3/mm^3)	1303	773	789
Body weight (g)	23.7	31.4	31.6
RW of the spleen	0.877	0.42	0.35
RW of the liver	6.9	5.0	4.7
RW of the kidney	1.5	1.36	1.82
RW of the lungs	1.14	1.14	1.25
RW of the heart	0.96	0.67	0.59

CIS: mice treated with ATG and cisplatin (ip, 17 mg/kg); hMSCs: mice treated with ATG, cisplatin (ip, 17 mg/kg), and hMSCs (iv, 0.5 × 10⁵ cells in 0.2 ml PBS); healthy: mice received PBS instead; WBC: white blood cells; RBC: red blood cells; PLT: platelets; RW: relative weight (weight of organ divided by body weight 100).