Review Article

Mesenchymal Stem and Progenitor Cells in Regeneration: Tissue Specificity and Regenerative Potential

Table 1

A selection of registered clinical trials on the basis of MSC as the relevant therapeutic tool (https://www.clinicaltrials.gov).

TitleRecruitmentConditionsPhasesInterventionSponsors

1Mesenchymal Stem Cells in Knee Cartilage InjuriesCompletedArticular
cartilage
disorder of knee
Phase IIBiological: autologous
mesenchymal stem cells
University of Jordan
2“One-Step” Bone Marrow Mononuclear Cell Transplantation in Talar Osteochondral LesionsRecruitingOsteochondritisPhase IIIProcedure: bone marrow cells transplantation on collagen scaffoldIstituto Ortopedico
Rizzoli
3Mesenchymal Stem Cell Based Therapy for the Treatment of Osteogenesis ImperfectaActive, not recruitingOsteogenesis
imperfecta
Phase IBiological: mesenchymal stem cellsHospital de Cruces;
Hospital Universitario
de Getafe; Hospital Infantil Universitario Niño Jesús, Madrid, Spain
4Treatment of Patients With Newly Onset of Type 1 Diabetes With Mesenchymal Stem CellsCompletedType 1 diabetes mellitusBiological: mesenchymal stem cellsUppsala University
Hospital
5Mesenchymal Stem Cells for Multiple SclerosisRecruitingMultiple
sclerosis
Phase I
Phase II
Drug: mesenchymal stem cells; drug: suspension mediaUniversity Hospital,
Toulouse
6Autologous Mesenchymal Stem Cells Transplantation in Cervical Chronic and Complete Spinal Cord InjuryRecruitingSpinal cord
injury
Phase IBiological: autologous mesenchymal cells transplantationHospital Sao Rafael