Clinical Study

Clinical Observation of Employment of Umbilical Cord Derived Mesenchymal Stem Cell for Juvenile Idiopathic Arthritis Therapy

Figure 4

Laboratory measurement before/after UC-MSC treatment in JIA patients. To test the effect of MSC treatment on JIA patients, two-time measurements were done at three months after the first MSC infusion (orange column) and at three months after the second infusion (green column). Values such as WBC, ESR, CRP, Tregs, IL-6, and TNF-α were analyzed and differences were compared with the values obtained before the MSC infusion (grey column). WBC, ESR, and CRP showed significant decreases, while Tregs showed a significant increase. The expression of IL-6 and TNF-α was declined at three months after the first and second UC-MSC infusion.